Background Fixed drug eruption (FDE) is a cutaneous adverse drug reaction characterized by erythematous plaques or blisters that recur at the same site upon re-exposure to the causative drug. It can leave residual pigmentation and, in severe cases, may present as generalized bullous fixed drug reaction (GBFDE). Objective The study aimed to evaluate the sensitivity of a standardized allergy workup for diagnosing the cause of FDE, with an emphasis on in situ repeated open application tests (ROATs). Methods A retrospective multicenter study analyzed the allergy workup practices for FDE diagnosis…
Read More