Tag: SJS/TEN

Drug vs Food Allergy: Immediate & Delayed Reactions

drugallergydetective.com
Infographic comparing drug vs food allergy: immediate (anaphylaxis) and delayed reactions; SJS/TEN uncommon with food.

Drug vs Food Allergy: Why Medications Can Cause Both Immediate and Delayed Reactions — While Foods Uncommonly Cause Severe Delayed Reactions This article is for educational purposes only. Always consult healthcare providers for personalized medical advice. Patients often ask:“Why can medications cause both rapid allergic reactions like hives or anaphylaxis and dangerous delayed reactions such as Stevens–Johnson Syndrome (SJS) or Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), while food allergies almost always appear immediately?” The difference lies in how the immune system processes drugs versus foods — and in…

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ROAT Patch Testing in SCARs: Is It Time to Reconsider?

drugallergydetective.com
Illustration symbolizing drug allergy testing with ROAT in severe cutaneous adverse reactions (SCARs) such as DRESS, AGEP, and FDE

Introduction Severe cutaneous adverse reactions (SCARs) — such as DRESS, AGEP, and SJS/TEN — are among the most serious drug hypersensitivity syndromes.The traditional approach is simple: avoid all suspected drugs indefinitely. But this blanket avoidance often creates real-world problems: This raises an important question:👉 Is it time to reconsider the role of patch testing — and even the Repeated Open Application Test (ROAT) — in managing SCARs? Why ROAT Is Feared in SCARs The Repeated Open Application Test (ROAT) is a simple diagnostic tool in delayed hypersensitivity: Concerns in SCARs:…

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